Download e-book for iPad: A Beginner's Guide to Blood Cells by Barbara J. Bain

By Barbara J. Bain

ISBN-10: 1405121750

ISBN-13: 9781405121750

This renowned notebook has been updated and expanded all through, delivering a concise view of diagnostic haematology, in a handy and useful format.

A Beginner's advisor to Blood Cells is a perfect for;

  • Trainee laboratory technicians and scientists
  • Students learning the body structure or pathology of the blood
  • Those getting ready for haematology examinations

Why purchase This Book?

  • Unique pocket advisor, written via Barbara Bain – a world-renowned specialist within the box of blood morphology
  • Outlines the fundamentals of diagnostic haematology
  • Includes a useful self-assessment section
  • NEW EDITION – now contains additional info on scientific features and extra tests
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Extra resources for A Beginner's Guide to Blood Cells

Example text

They contain iron and when this is confirmed by an iron stain they are referred to as siderotic granules. Basophilic stippling refers to the presence of small basophilic inclusions distributed throughout the red cell (Fig. 27). They do not contain iron but represent abnormally staining ribosomes. Howell–Jolly bodies (Fig. 28) are larger, round, densely staining inclusions, usually towards one edge of the cell. They represent a nuclear fragment that was not extruded when the red cell left the bone marrow.

Characteristic morphological changes occur in lymphocytes in different types of leukaemia and lymphoma (see Chapter 4). Assessing morphology of monocytes, eosinophils and basophils Numerical changes in monocytes, eosinophils and basophils are often useful in diagnosis but this is less often the case with morphological changes. Monocytes can show increased size and cytoplasmic vacuolation during infection. Immature monocytes with increased gran- Fig. 11 Eosinophil leucocytosis with one of the three eosinophils being markedly hypogranular.

1 and illustrated in Fig. 22. 1 Definitions of cells by shape. Spherocyte Microspherocyte Irregularly contracted cell Elliptocyte Ovalocyte Dacrocyte (tear-drop poikilocyte) Target cell Stomatocyte Keratocyte Schistocyte (red cell fragment) Echinocyte (crenated cell) Acanthocyte Sickle cell Boat-shaped cell SC poikilocyte Cell which is approximately spherical in shape so that it has lost its central pallor; the cell outline is regular Spherocyte of reduced size and therefore diameter Cell of reduced size and diameter with a lack of central pallor but with an irregular outline Cell with an elliptical outline Cell with an oval outline Cell shaped like a tear-drop Cell with a more strongly staining area in the centre of the area of central pallor Cell with a central slit or stoma Cell with two or four curved horn-shaped projections Fragment of a cell, usually angular; a microspherocyte is a particular type of schistocyte Cell with its surface covered with 20–30 small, regular, blunt projections Cell with its surface covered with two to twenty projections of irregular shape and irregularly distributed Cell with a sickle or crescent shape, caused by the presence of a high concentration of an abnormal haemoglobin known as haemoglobin S Cell similar in shape to an elliptocyte but with both ends pointed, usually indicative of the presence of haemoglobin S Bizarre poikilocyte formed when cells contain both haemoglobin S and haemoglobin C, having some curved edges and some square or rectangular protrusions Fig.

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A Beginner's Guide to Blood Cells by Barbara J. Bain

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